Antihypertensive effects of lofexidine in patients with essential hypertension.

1 Single oral doses of lofexidine, 0.1, 0.3, and 0.6 mg produced dose related decreases in supine and standing arterial pressure and heart rate in nineteen patients with essential hypertension. 2 A mean oral antihypertensive threshold dose of less than 0.1 mg was estimated. 3 Lofexidine decreased me...

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Main Authors: Fagan, T C, Bloomfield, S S, Cowart, T D, Corns-Hurwitz, R H, Lipicky, R J, Conradi, E C, Hsu, C Y, Grossman, W J, Harmon, G E, Degenhart, W J, Sinkfield, A W, Gaffney, T E
Format: Artigo
Language:Inglês
Published: 1982
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1402104/
https://ncbi.nlm.nih.gov/pubmed/7059442
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