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Specificity of Cdk activation in vivo by the two Caks Mcs6 and Csk1 in fission yeast

Activating phosphorylation of cyclin-dependent kinases (Cdks) is mediated by at least two structurally distinct types of Cdk-activating kinases (Caks): the trimeric Cdk7–cyclin H–Mat1 complex in metazoans and the single-subunit Cak1 in budding yeast. Fission yeast has both Cak types: Mcs6 is a Cdk7...

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Autores principales: Hermand, Damien, Westerling, Thomas, Pihlak, Arno, Thuret, Jean-Yves, Vallenius, Tea, Tiainen, Marianne, Vandenhaute, Jean, Cottarel, Guillaume, Mann, Carl, Mäkelä, Tomi P.
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2001
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC140202/
https://ncbi.nlm.nih.gov/pubmed/11226158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.1.82
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