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Sec63p and Kar2p are required for the translocation of SRP-dependent precursors into the yeast endoplasmic reticulum in vivo

The translocation of secretory polypeptides into the endoplasmic reticulum (ER) occurs at the translocon, a pore-forming structure that orchestrates the transport and maturation of polypeptides at the ER membrane. In yeast, targeting of secretory precursors to the translocon can occur by two distinc...

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Détails bibliographiques
Publié dans:EMBO J
Auteurs principaux: Young, Barry P., Craven, Rachel A., Reid, Peter J., Willer, Martin, Stirling, Colin J.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2001
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC140194/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11226176/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.1.262
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