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Effects of microsomal enzyme induction on paracetamol metabolism in man.

1 The metabolism of paracetamol after a single oral dose of 20 mg/kg was compared in fifteen patients with microsomal enzyme induction taking anticonvulsants or rifampicin and twelve healthy volunteers. 2 Induction was confirmed by measurement of the plasma antipyrine half-life (mean 6.4 h in the pa...

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Detalhes bibliográficos
Main Authors: Prescott, L F, Critchley, J A, Balali-Mood, M, Pentland, B
Formato: Artigo
Idioma:Inglês
Publicado em: 1981
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1401868/
https://ncbi.nlm.nih.gov/pubmed/7306429
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