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Metabolism and pharmacokinetics of dothiepin.

1 Seven healthy volunteers received a single oral dose of 75 mg dothiepin. Plasma concentrations of dothiepin were measured by gas chromatography-mass fragmentography. 2 The plasma concentrations obtained were fitted to the equation Ct = Ae-a(t-tau) + Be-beta(t-tau) - Ce-ka(t-tau). The mean peak con...

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Detalhes bibliográficos
Main Authors: Maguire, K P, Burrows, G D, Norman, T R, Scoggins, B A
Formato: Artigo
Idioma:Inglês
Publicado em: 1981
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1401810/
https://ncbi.nlm.nih.gov/pubmed/7295471
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