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A specific radioenzymatic assay for dihydroxyphenylalanine (DOPA). Plasma dopa may be the precursor of urine free dopamine.

1 A sensitive radioenzymatic assay was developed, in which DOPA is enzymatically decarboxylated to dopamine and the latter converted to [3H]-methoxytyramine in the presence of [3H]-S-adenosyl-L-methionine and catechol-o-methyltransferase. 2 The assay was specific for DOPA, and was sensitive to 50 pg...

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Detalhes bibliográficos
Main Authors: Brown, M J, Dollery, C T
Formato: Artigo
Idioma:Inglês
Publicado em: 1981
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1401704/
https://ncbi.nlm.nih.gov/pubmed/6783056
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