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Circadian variations in the signs and symptoms of rheumatoid arthritis and in the therapeutic effectiveness of flurbiprofen at different times of day.

1 Seventeen patients with rheumatoid arthritis were studied in a double-blind crossover trial contrasting three different times of administration of twice-daily flurbiprofen. 2 Twelve of these patients were also studied when taking the same dose of flurbiprofen as a split dose four times a day. 3 Sy...

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Autores principales: Kowanko, I C, Pownall, R, Knapp, M S, Swannell, A J, Mahoney, P G
Formato: Artigo
Lenguaje:Inglês
Publicado: 1981
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1401588/
https://ncbi.nlm.nih.gov/pubmed/7272159
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