The neutrophil-activating protein of Helicobacter pylori promotes Th1 immune responses

The Helicobacter pylori neutrophil-activating protein (HP-NAP) is a virulence factor of H. pylori that stimulates in neutrophils high production of oxygen radicals and adhesion to endothelial cells. We report here that HP-NAP is a TLR2 agonist able to induce the expression of IL-12 and IL-23 by neut...

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Main Authors: Amedei, Amedeo, Cappon, Andrea, Codolo, Gaia, Cabrelle, Anna, Polenghi, Alessandra, Benagiano, Marisa, Tasca, Elisabetta, Azzurri, Annalisa, D’Elios, Mario Milco, Del Prete, Gianfranco, de Bernard, Marina
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 2006
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1401483/
https://ncbi.nlm.nih.gov/pubmed/16543949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI27177
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