Inhibitory effects of neuroleptics on debrisoquine oxidation in man.

Liver oxidative metabolism, assessed by debrisoquine hydroxylation test, was studied in 107 healthy volunteers and in 71 patients with or without neuroleptic drug treatment. The mean metabolic ratio (MR = debrisoquine/4-hydroxydebrisoquine excretion in the urine) was 2.8 +/- 0.1 (s.e. mean) in the c...

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Detaylı Bibliyografya
Asıl Yazarlar: Syvälahti, E K, Lindberg, R, Kallio, J, De Vocht, M
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1986
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1401082/
https://ncbi.nlm.nih.gov/pubmed/2874826
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