Cardiovascular toxicity and distribution kinetics of intravenous chloroquine.

Chloroquine diphosphate (3 mg base kg-1) was given by constant rate intravenous injection over 10 min to 12 healthy adult male volunteers. Plasma concentrations of chloroquine and the principal metabolite desethylchloroquine, electrocardiograph intervals, and arterial blood pressure were measured at...

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Bibliografiske detaljer
Main Authors: Looareesuwan, S, White, N J, Chanthavanich, P, Edwards, G, Nicholl, D D, Bunch, C, Warrell, D A
Format: Artigo
Sprog:Inglês
Udgivet: 1986
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1401074/
https://ncbi.nlm.nih.gov/pubmed/3741724
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