The pharmacokinetics of R- and S-tocainide in patients with acute ventricular arrhythmias.

The pharmacokinetics of R(-) and S(+)- tocainide were studied in twelve patients requiring intravenous tocainide. In all patients, a progressive increase in the S(+):R(-) ratio was observed during the infusion. Mean +/- s.d. ratios increased from 1.03 +/- 0.05 at 2 min to 1.76 +/- 0.35 at 48.5 h. Da...

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Bibliographic Details
Main Authors: Thomson, A H, Murdoch, G, Pottage, A, Kelman, A W, Whiting, B, Hillis, W S
Format: Artigo
Language:Inglês
Published: 1986
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1400923/
https://ncbi.nlm.nih.gov/pubmed/3082345
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