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Propynyl groups in duplex DNA: stability of base pairs incorporating 7-substituted 8-aza-7-deazapurines or 5-substituted pyrimidines

Oligonucleotides incorporating the 7-propynyl derivatives of 8-aza-7-deaza-2′-deoxyguanosine (3b) and 8-aza-7-deaza-2′-deoxyadenosine (4b) were synthesized and their duplex stability was compared with those containing the 5-propynyl derivatives of 2′-deoxycytidine (1) and 2′-deoxyuridine (2). For th...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Principais autores: He, Junlin, Seela, Frank
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2002
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC140073/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12490717/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkf689
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