Azathioprine suppresses the mixed lymphocyte reaction of patients with Lesch-Nyhan syndrome.

The mixed lymphocyte reaction of Lesch-Nyhan patients (HGPRT deficient) was used to study the immunosuppressive effects of azathioprine and 6-mercaptopurine (6-MP). Mitogen stimulated lymphocytes of these patients are highly resistant to azathioprine and 6-MP. When both stimulator and responder lymp...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Szawlowski, P W, Al-Safi, S A, Dooley, T, Maddocks, J L
Format: Artigo
Langue:Inglês
Publié: 1985
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1400706/
https://ncbi.nlm.nih.gov/pubmed/2934083
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