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Selectivity and dose-dependency of the inhibitory effect of propranolol on theophylline metabolism in man.

The effects of separate 5 day pretreatments of propranolol 120 mg day-1 and 720 mg day-1 on theophylline clearance and metabolism at steady-state were determined in seven healthy males. Propranolol 120 mg day-1 decreased theophylline plasma clearance (CL) by 30%. Clearance of theophylline to each me...

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Autors principals: Miners, J O, Wing, L M, Lillywhite, K J, Robson, R A
Format: Artigo
Idioma:Inglês
Publicat: 1985
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1400697/
https://ncbi.nlm.nih.gov/pubmed/4041342
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