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Anti-HIV-1 activity of anionic polymers: a comparative study of candidate microbicides
BACKGROUND: Cellulose acetate phthalate (CAP) in soluble form blocks coreceptor binding sites on the virus envelope glycoprotein gp120 and elicits gp41 six-helix bundle formation, processes involved in virus inactivation. CAP is not soluble at pH < 5.5, normal for microbicide target sites. Theref...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC139971/ https://ncbi.nlm.nih.gov/pubmed/12445331 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2334-2-27 |
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