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Efficient synthesis of 5-substituted 2-aryl-6-cyanoindolizines via nucleophilic substitution reactions

2-Aryl-6-cyano-7-methyl-5-indolizinones were successfully converted into 2-aryl-5-chloro-6-cyano-7-methylindolizines. The obtained 5-chloroindolizines readily underwent nucleophilic substitution at position 5 leading in high yields to novel 5-functionalised indolizines.

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Bibliographische Detailangaben
Hauptverfasser: Babaev, Eugene V, Vasilevich, Natalya I, Ivushkina, Anna S
Format: Artigo
Sprache:Inglês
Veröffentlicht: Beilstein-Institut 2005
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1399457/
https://ncbi.nlm.nih.gov/pubmed/16542026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1860-5397-1-9
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