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Flaws in design, analysis and interpretation of Pfizer's antifungal trials of voriconazole and uncritical subsequent quotations

We have previously described how a series of trials sponsored by Pfizer of its antifungal drug, fluconazole, in cancer patients with neutropenia handicapped the control drug, amphotericin B, by flaws in design and analysis. We describe similar problems in two pivotal trials of Pfizer's new anti...

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Detalhes bibliográficos
Main Authors: Jørgensen, Karsten J, Johansen, Helle Krogh, Gøtzsche, Peter C
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1399447/
https://ncbi.nlm.nih.gov/pubmed/16542031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1745-6215-7-3
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