Downregulation of c-Jun Expression by Transcription Factor C/EBPα Is Critical for Granulocytic Lineage Commitment

The transcription factor C/EBPα is crucial for the differentiation of granulocytes. Conditional expression of C/EBPα triggers neutrophilic differentiation, and C/EBPα can block 12-O-tetradecanoylphorbol-13-acetate-induced monocytic differentiation of bipotential myeloid cells. In C/EBPα knockout mic...

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Bibliographic Details
Main Authors: Rangatia, Janki, Vangala, Rajani Kanth, Treiber, Nicolai, Zhang, Pu, Radomska, Hanna, Tenen, Daniel G., Hiddemann, Wolfgang, Behre, Gerhard
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2002
Subjects:
Transcriptional Regulation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC139872/
https://ncbi.nlm.nih.gov/pubmed/12446786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.24.8681-8694.2002
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