Redundancy in Tumor Necrosis Factor (TNF) and Lymphotoxin (LT) Signaling In Vivo: Mice with Inactivation of the Entire TNF/LT Locus versus Single-Knockout Mice

Homologous genes and gene products often have redundant physiological functions. Members of the tumor necrosis factor (TNF) family of cytokines can signal activation, proliferation, differentiation, costimulation, inhibition, or cell death, depending on the type and status of the target cell. TNF, l...

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Podrobná bibliografie

Vydáno v:	Mol Cell Biol
Hlavní autoři:	Kuprash, Dmitry V., Alimzhanov, Marat B., Tumanov, Alexei V., Grivennikov, Sergei I., Shakhov, Alexander N., Drutskaya, Ludmila N., Marino, Michael W., Turetskaya, Regina L., Anderson, Arthur O., Rajewsky, Klaus, Pfeffer, Klaus, Nedospasov, Sergei A.
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Taylor & Francis 2002
Témata:	Mammalian Genetic Models with Minimal or Complex Phenotypes
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC139867/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12446781/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.24.8626-8634.2002
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