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Differential Regulation of E2F1, DP1, and the E2F1/DP1 Complex by ARF
The tumor suppressor protein ARF inhibits MDM2 to activate and stabilize p53. Recent studies provided evidence for p53-independent tumor suppression functions of ARF. For example, it has been shown that ARF induces proteolysis of certain E2F species, including E2F1. In addition, ARF relocalizes E2F1...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Microbiology
2002
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC139864/ https://ncbi.nlm.nih.gov/pubmed/12446760 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.24.8398-8408.2002 |
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