Grit, a GTPase-Activating Protein for the Rho Family, Regulates Neurite Extension through Association with the TrkA Receptor and N-Shc and CrkL/Crk Adapter Molecules

Neurotrophins are key regulators of the fate and shape of neuronal cells and act as guidance cues for growth cones by remodeling the actin cytoskeleton. Actin dynamics is controlled by Rho GTPases. We identified a novel Rho GTPase-activating protein (Grit) for Rho/Rac/Cdc42 small GTPases. Grit was a...

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Publié dans:	Mol Cell Biol
Auteurs principaux:	Nakamura, Takeshi, Komiya, Misako, Sone, Kiyoaki, Hirose, Eiji, Gotoh, Noriko, Morii, Hiroshi, Ohta, Yasutaka, Mori, Nozomu
Format:	Artigo
Langue:	Inglês
Publié:	Taylor & Francis 2002
Sujets:	Cell Growth and Development
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC139861/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12446789/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.24.8721-8734.2002
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