Association of DNA Polymerase μ (pol μ) with Ku and Ligase IV: Role for pol μ in End-Joining Double-Strand Break Repair

Mammalian DNA polymerase μ (pol μ) is related to terminal deoxynucleotidyl transferase, but its biological role is not yet clear. We show here that after exposure of cells to ionizing radiation (IR), levels of pol μ protein increase. pol μ also forms discrete nuclear foci after IR, and these foci ar...

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Bibliografiske detaljer
Main Authors: Mahajan, Kiran N., Nick McElhinny, Stephanie A., Mitchell, Beverly S., Ramsden, Dale A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2002
Fag:
DNA Dynamics and Chromosome Structure
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC139779/
https://ncbi.nlm.nih.gov/pubmed/12077346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.14.5194-5202.2002
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