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Mammalian PRP4 Kinase Copurifies and Interacts with Components of Both the U5 snRNP and the N-CoR Deacetylase Complexes

A growing body of evidence supports the coordination of pre-mRNA processing and transcriptional regulation. We demonstrate here that mammalian PRP4 kinase (PRP4K) is associated with complexes involved in both of these processes. PRP4K is implicated in pre-mRNA splicing as the homologue of the Schizo...

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Pubblicato in:Mol Cell Biol
Autori principali: Dellaire, Graham, Makarov, Evgeny M., Cowger, JeffJ.M., Longman, Dasa, Sutherland, Heidi G. E., Lührmann, Reinhard, Torchia, Joseph, Bickmore, Wendy A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2002
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC139773/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12077342/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.14.5141-5156.2002
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