Obligate Roles for p16(Ink4a) and p19(Arf)-p53 in the Suppression of Murine Pancreatic Neoplasia

Epithelial tumors of the pancreas exhibit a wide spectrum of histologies with varying propensities for metastasis and tissue invasion. The histogenic relationship among these tumor types is not well established; moreover, the specific role of genetic lesions in the progression of these malignancies...

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Bibliographic Details
Main Authors: Bardeesy, Nabeel, Morgan, Jeffrey, Sinha, Manisha, Signoretti, Sabina, Srivastava, Shefali, Loda, Massimo, Merlino, Glenn, DePinho, Ronald A.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2002
Subjects:
Cell Growth and Development
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC139752/
https://ncbi.nlm.nih.gov/pubmed/11756558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.2.635-643.2002
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