Effect of Redox Balance Alterations on Cellular Localization of LAT and Downstream T-Cell Receptor Signaling Pathways

The integral membrane protein linker for activation of T cells (LAT) is a central adapter protein in the T-cell receptor (TCR)-mediated signaling pathways. The cellular localization of LAT is extremely sensitive to intracellular redox balance alterations. Reduced intracellular levels of the antioxid...

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Main Authors: Gringhuis, Sonja I., Papendrecht-van der Voort, Ellen A. M., Leow, Angela, Levarht, E. W. Nivine, Breedveld, Ferdinand C., Verweij, Cornelis L.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2002
Assuntos:
Cell Growth and Development
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC139732/
https://ncbi.nlm.nih.gov/pubmed/11756537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.2.400-411.2002
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