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HSV-mediated expression of interleukin-4 in dorsal root ganglion neurons reduces neuropathic pain

BACKGROUND: To examine the role of inflammatory mediators in neuropathic pain, we used a replication-defective genomic herpes simplex virus (HSV)-based vector containing the coding sequence for the anti-inflammatory peptide interleukin (IL)-4 under the transcriptional control of the HSV ICP4 immedia...

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Autores principales: Hao, Shuanglin, Mata, Marina, Glorioso, Joseph C, Fink, David J
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2006
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1395302/
https://ncbi.nlm.nih.gov/pubmed/16503976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-2-6
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