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Caretaker Brca1: keeping the genome in the straight and narrow

Inheritance of germline BRCA1 mutations is associated with a high risk of breast and ovarian cancers. A multitude of cellular functions has been ascribed to BRCA1, including transcription activation and various aspects of DNA repair. So far, indirect evidence has indicated a role for BRCA1 in the re...

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Detalhes bibliográficos
Autor principal: Yu, Veronica
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC139427/
https://ncbi.nlm.nih.gov/pubmed/11250695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr37
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