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Control of Substrate Specificity by Active-Site Residues in Nitrobenzene Dioxygenase

Nitrobenzene 1,2-dioxygenase from Comamonas sp. strain JS765 catalyzes the initial reaction in nitrobenzene degradation, forming catechol and nitrite. The enzyme also oxidizes the aromatic rings of mono- and dinitrotoluenes at the nitro-substituted carbon, but the basis for this specificity is not u...

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Detalhes bibliográficos
Main Authors: Ju, Kou-San, Parales, Rebecca E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1393210/
https://ncbi.nlm.nih.gov/pubmed/16517627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.72.3.1817-1824.2006
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