Effective Detection of Toxigenic Clostridium difficile by a Two-Step Algorithm Including Tests for Antigen and Cytotoxin

We evaluated a two-step algorithm for detecting toxigenic Clostridium difficile: an enzyme immunoassay for glutamate dehydrogenase antigen (Ag-EIA) and then, for antigen-positive specimens, a concurrent cell culture cytotoxicity neutralization assay (CCNA). Antigen-negative results were ≥99% predict...

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Detalhes bibliográficos
Main Authors: Ticehurst, John R., Aird, Deborah Z., Dam, Lisa M., Borek, Anita P., Hargrove, John T., Carroll, Karen C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Bacteriology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1393084/
https://ncbi.nlm.nih.gov/pubmed/16517916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.44.3.1145-1149.2006
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