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Production of the Lantibiotic Salivaricin A and Its Variants by Oral Streptococci and Use of a Specific Induction Assay To Detect Their Presence in Human Saliva

Salivaricin A (SalA), the first Streptococcus salivarius lantibiotic to be characterized, appears to be inhibitory to most Streptococcus pyogenes strains. A variant of the SalA structural gene (salA1) is present in more than 90% of S. pyogenes strains, but only strains of M serotype 4 and T pattern...

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Detalhes bibliográficos
Main Authors: Wescombe, Philip A., Upton, Mathew, Dierksen, Karen P., Ragland, Nancy L., Sivabalan, Senthuran, Wirawan, Ruth E., Inglis, Megan A., Moore, Chris J., Walker, Glenn V., Chilcott, Chris N., Jenkinson, Howard F., Tagg, John R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1392966/
https://ncbi.nlm.nih.gov/pubmed/16461700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.72.2.1459-1466.2006
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