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Can the Ca(2+) hypothesis and the Ca(2+)-voltage hypothesis for neurotransmitter release be reconciled?

It is well established that Ca(2+) plays a key role in promoting the physiological depolarization-induced release (DIR) of neurotransmitters from nerve terminals (Ca(2+) hypothesis). Yet, evidence has accumulated for the Ca(2+)-voltage hypothesis, which states that not only is Ca(2+) required, but m...

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Detalles Bibliográficos
Main Authors: Parnas, Hanna, Valle-Lisboa, J.-C., Segel, Lee A.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2002
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC139284/
https://ncbi.nlm.nih.gov/pubmed/12486235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.242549999
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