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High Analytical Sensitivity and Low Rates of Inhibition May Contribute to Detection of Chlamydia trachomatis in Significantly More Women by the APTIMA Combo 2 Assay

The clinical sensitivity of nucleic acid amplification tests may be determined by analytical sensitivity and inhibitors in patient samples. We established endpoints for detection of propagated Chlamydia trachomatis L2 434, diluted according to swab and urine protocols for APTIMA Combo 2 (AC2), Probe...

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Detalhes bibliográficos
Main Authors: Chernesky, Max, Jang, Dan, Luinstra, Kathy, Chong, Sylvia, Smieja, Marek, Cai, Wenjie, Hayhoe, Beth, Portillo, Eder, MacRitchie, Cindy, Main, Cheryl, Ewert, Ruth
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1392683/
https://ncbi.nlm.nih.gov/pubmed/16455891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.44.2.400-405.2006
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