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An ensemble method for identifying regulatory circuits with special reference to the qa gene cluster of Neurospora crassa

A chemical reaction network for the regulation of the quinic acid (qa) gene cluster of Neurospora crassa is proposed. An efficient Monte Carlo method for walking through the parameter space of possible chemical reaction networks is developed to identify an ensemble of deterministic kinetics models w...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Battogtokh, D., Asch, D. K., Case, M. E., Arnold, J., Schüttler, H.-B.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2002
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC139242/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12477937/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.262658899
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