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Genetic variation in the 22q11 locus and susceptibility to schizophrenia

An increased prevalence of microdeletions at the 22q11 locus has been reported in samples of patients with schizophrenia. 22q11 microdeletions represent the highest known genetic risk factor for the development of schizophrenia, second only to that of the monozygotic cotwin of an affected individual...

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Published in:Proc Natl Acad Sci U S A
Main Authors: Liu, Hui, Abecasis, Gonçalo R., Heath, Simon C., Knowles, Alyson, Demars, Sandra, Chen, Ying-Jiun, Roos, J. Louw, Rapoport, Judith L., Gogos, Joseph A., Karayiorgou, Maria
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2002
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC139234/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12477929/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.232186099
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