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Polyphosphate kinase (PPK2), a potent, polyphosphate-driven generator of GTP

An enzyme that uses inorganic polyphosphate (poly P) as a donor to convert GDP to GTP has been purified 1,300-fold to homogeneity from lysates of Pseudomonas aeruginosa PAOM5. Poly P chains of 30–50 residues are optimal; those of 15–700 residues can also serve. GDP is preferred over ADP among nucleo...

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Publicado en:Proc Natl Acad Sci U S A
Autores principales: Ishige, Kazuya, Zhang, Haiyu, Kornberg, Arthur
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2002
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC139204/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12482933/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.262655299
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