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Endotoxin Contamination in Commercially Available Pokeweed Mitogen Contributes to the Activation of Murine Macrophages and Human Dendritic Cell Maturation

Commercially available pokeweed mitogen (PWM) has been reported to activate macrophages, leading to production of proinflammatory cytokines and nitric oxide (NO). However, we found that polymyxin B (PMB), a specific inhibitor of endotoxin activity, inhibited the PWM-induced expression of proinflamma...

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Detalhes bibliográficos
Main Authors: Yang, Jae Seung, Kim, Hye Jin, Ryu, Young Hee, Yun, Cheol-Heui, Chung, Dae Kyun, Han, Seung Hyun
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1391957/
https://ncbi.nlm.nih.gov/pubmed/16522770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.13.3.309-313.2006
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