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SCL/tal-1-dependent process determines a competence to select the definitive hematopoietic lineage prior to endothelial differentiation

Hematopoiesis in most vertebrate species occurs in two distinct phases, primitive and definitive, which diverge from FLK1(+)VE-cadherin(–) mesoderm and FLK1(+)VE-cadherin(+) endothelial cells (EC), respectively. This study aimed at determining the stage at which hematopoietic lineage fate is determi...

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Détails bibliographiques
Auteurs principaux: Endoh, Mitsuhiro, Ogawa, Minetaro, Orkin, Stuart, Nishikawa, Shin-ichi
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2002
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC139094/
https://ncbi.nlm.nih.gov/pubmed/12485991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf674
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