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An inserted region of leucyl-tRNA synthetase plays a critical role in group I intron splicing

Yeast mitochondrial leucyl-tRNA synthetase (LeuRS) binds to the bI4 intron and collaborates with the bI4 maturase to aid excision of the group I intron. Deletion analysis isolated the inserted LeuRS CP1 domain as a critical factor in the protein’s splicing activity. Protein fragments comprised of ju...

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Bibliographic Details
Published in:EMBO J
Main Authors: Rho, Seung Bae, Lincecum, Tommie L., Martinis, Susan A.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2002
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC139092/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12486008/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdf671
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