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The evolutionary history of effectors downstream of Cdc42 and Rac

Cdc42 and Rac - ancient, highly conserved, small GTPases - mediate extracellular signals, triggering changes in transcription and in the actin cytoskeleton. Although dozens of proteins act downstream of these GTPases, a comparison of effector proteins from evolutionarily diverse organisms suggests t...

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Bibliographic Details
Published in:Genome Biol
Main Authors: Cotteret, Sophie, Chernoff, Jonathan
Format: Artigo
Language:Inglês
Published: BMC 2002
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC139012/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11864373/
https://ncbi.nlm.nih.govhttps://doi.org/10.1186/gb-2002-3-2-reviews0002
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