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New Positive Regulators of lin-12 Activity in Caenorhabditis elegans Include the BRE-5/Brainiac Glycosphingolipid Biosynthesis Enzyme
Screens for suppressors of lin-12 hypermorphic alleles in C. elegans have identified core components and modulators of the LIN-12/Notch signaling pathway. Here we describe the recovery of alleles of six new genes from a screen for suppressors of the egg-laying defect associated with elevated lin-12...
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| Format: | Artigo |
| Sprache: | Inglês |
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Copyright © 2005 by the Genetics Society of America
2005
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1389698/ https://ncbi.nlm.nih.gov/pubmed/16157663 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.105.048041 |
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