Purification and Characterization of a Lovastatin Esterase from Clonostachys compactiuscula

An esterase from the fungus Clonostachys compactiuscula selectively hydrolyzes lovastatin, a clinically useful antihypercholesterolemic agent. Lovastatin or lovastatin-related compounds were required to induce the activity of the lovastatin 8(prm1)-((alpha)-methylbutyryloxy) esterase. The 46-kDa est...

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Autors principals: Schimmel, T. G., Borneman, W. S., Conder, M. J.
Format: Artigo
Idioma:Inglês
Publicat: 1997
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1389545/
https://ncbi.nlm.nih.gov/pubmed/16535567
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