Neuronal intranuclear inclusions are ultrastructurally and immunologically distinct from cytoplasmic inclusions of neuronal intermediate filament inclusion disease

Abnormal neuronal cytoplasmic inclusions (NCIs) containing aggregates of α-internexin and the neurofilament (NF) subunits, NF-H, NF-M, and NF-L, are the signature lesions of neuronal intermediate filament (IF) inclusion disease (NIFID). The disease has a clinically heterogeneous phenotype, including...

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Main Authors: Mosaheb, Sabrina, Thorpe, Julian R., Hashemzadeh-Bonehi, Lida, Bigio, Eileen H., Gearing, Marla, Cairns, Nigel J.
Format: Artigo
Jezik:Inglês
Izdano: 2005
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1388263/
https://ncbi.nlm.nih.gov/pubmed/16025283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-005-1057-x
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