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BMP inhibition-driven regulation of six-3 underlies induction of newt lens regeneration

Lens regeneration in adult newts is a classic example of faithfully regenerating an entire organ via transdifferentiation1–6. After lentectomy, intriguing regulation allows the pigment epithelial cells (PECs) of the dorsal iris, but not the ventral, to dedifferentiate and then differentiate to form...

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Hlavní autoři: Grogg, Matthew W., Call, Mindy K., Okamoto, Mitsumasa, Vergara, M. Natalia, Del Rio-Tsonis, Katia, Tsonis, Panagiotis A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2005
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1388258/
https://ncbi.nlm.nih.gov/pubmed/16341014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature04175
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