Alterations in vasodilator-stimulated phosphoprotein (VASP) phosphorylation: associations with asthmatic phenotype, airway inflammation and β(2)-agonist use

BACKGROUND: Vasodilator-stimulated phosphoprotein (VASP) mediates focal adhesion, actin filament binding and polymerization in a variety of cells, thereby inhibiting cell movement. Phosphorylation of VASP via cAMP and cGMP dependent protein kinases releases this "brake" on cell motility. T...

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Autors principals: Hastie, Annette T, Wu, Min, Foster, Gayle C, Hawkins, Gregory A, Batra, Vikas, Rybinski, Katherine A, Cirelli, Rosemary, Zangrilli, James G, Peters, Stephen P
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2006
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1388207/
https://ncbi.nlm.nih.gov/pubmed/16480498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-7-25
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