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Chlorzoxazone metabolism is increased in fasted Sprague-Dawley rats

Earlier data showed that men fasted for 38 h have a reduced rate of chlorzoxazone (CZ) metabolism suggesting a decreased level of cytochrome P450 2E1 (CYP2E1). In contrast, CYP2E1 level in fasted rats has been shown to be elevated. In this study, we investigated whether CZ metabolism in fasted rats...

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Main Authors: Wan, Jie, Ernstgård, Lena, Song, Byoung J., Shoaf, Susan E.
Formato: Artigo
Idioma:Inglês
Publicado: 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1388188/
https://ncbi.nlm.nih.gov/pubmed/16393464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1211/jpp.58.1.0007
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