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Ipr1 gene mediates innate immunity to tuberculosis

An estimated 8 million people are infected each year with the pathogen, Mycobacterium tuberculosis, and over 2 million die annually1. Yet only about 10% of those infected develop tuberculosis. Genetic variation within host populations is known to play a significant role in humans and animals 2,3, bu...

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Hlavní autoři: Pan, Hui, Yan, Bo-Shiun, Rojas, Mauricio, Shebzukhov, Yuriy V., Zhou, Hongwei, Kobzik, Lester, Higgins, Darren, Daly, Mark, Bloom, Barry R., Kramnik, Igor
Médium: Artigo
Jazyk:Inglês
Vydáno: 2005
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1388092/
https://ncbi.nlm.nih.gov/pubmed/15815631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature03419
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