Differential Roles of S6 Domain Hinges in the Gating of KCNQ Potassium Channels

Voltage-gated K(+) channel activation is proposed to result from simultaneous bending of all S6 segments away from the central axis, enlarging the aperture of the pore sufficiently to permit diffusion of K(+) into the water-filled central cavity. The hinge position for the bending motion of each S6...

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Autori principali: Seebohm, Guiscard, Strutz-Seebohm, Nathalie, Ureche, Oana N., Baltaev, Ravshan, Lampert, Angelika, Kornichuk, Ganna, Kamiya, Kaichiro, Wuttke, Thomas V., Lerche, Holger, Sanguinetti, Michael C., Lang, Florian
Natura: Artigo
Lingua:Inglês
Pubblicazione: Biophysical Society 2006
Soggetti:
Electrophysiology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1386802/
https://ncbi.nlm.nih.gov/pubmed/16326905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.067165
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