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Force Unfolding Single RNAs

We develop a continue time Monte Carlo algorithm to simulate single RNAs unfolded by a time-dependent external force on the secondary structure level. Two recent unfolding RNA experiments carried out by Bustamante group are mainly investigated. We find that, in contrast to popular two-state assumpti...

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Bibliografiske detaljer
Main Authors: Liu, Fei, Tong, Huan, Ou-Yang, Zhong-can
Format: Artigo
Sprog:Inglês
Udgivet: Biophysical Society 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1386770/
https://ncbi.nlm.nih.gov/pubmed/16387784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.070540
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