The relationship between inhibition of vitamin K1 2,3-epoxide reductase and reduction of clotting factor activity with warfarin.

1 The effect of low dose steady state warfarin (0.2 mg and 1 mg daily) on clotting factor activity and vitamin K1 metabolism was studied in seven healthy volunteers. 2 Steady state plasma warfarin concentrations were 41-99 ng ml-1 for the 0.2 mg dose and 157-292 ng ml-1 for the 1 mg dose. 3 There wa...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Choonara, I A, Malia, R G, Haynes, B P, Hay, C R, Cholerton, S, Breckenridge, A M, Preston, F E, Park, B K
Format: Artigo
Langue:Inglês
Publié: 1988
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1386607/
https://ncbi.nlm.nih.gov/pubmed/3370190
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