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Extended blood collection period required to define distribution and elimination kinetics of propofol.

The pharmacokinetics of propofol were investigated following bolus intravenous administration of 2-3 mg kg-1 of drug to eight surgical patients. Apparent elimination half-life, volume of distribution and systemic blood clearance of propofol correlated strongly with the sampling period, which ranged...

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Detalhes bibliográficos
Main Authors: Campbell, G A, Morgan, D J, Kumar, K, Crankshaw, D P
Formato: Artigo
Idioma:Inglês
Publicado em: 1988
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1386527/
https://ncbi.nlm.nih.gov/pubmed/3264711
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